Made
GPM6A
Locus Rank
78

Gene

Id
230
Gene Name
GPM6A
Duplicated
True
Maternal
False
Gene Not Within Locus (Nearby
False
Gene Description
Mouse Phenotype
Additional Image
Allen Brain
Allen Regions
Zfin In Situ
Zfin Brain Areas
anterior lateral line ganglion, central nervous system, cranial ganglion, diencephalon, epiphysis, hindbrain, nucleus of the tract of the postoptic commissure, optic tectum, optic tract, optic vesicle, periventricular grey zone, posterior lateral line ganglion, retina, retinal ganglion cell layer, retinal inner nuclear layer, Rohon-Beard neuron, spinal cord, statoacoustic (VIII) ganglion, telencephalon, trigeminal ganglion, trigeminal placode
Published Zebrafish Pehnotype
Not In Allen Brain
False
ZFIN Link
http://zfin.org/search?q=gpm6a&fq=category%3A%22Gene+%2F+Transcript%22&category=Gene+%2F+Transcript&fq=type%3A%22Gene%22
Allen Link
http://mouse.brain-map.org/gene/show/87807
More Additional Images
Papers
http://www.ncbi.nlm.nih.gov/pubmed/25242528

Locus Rank

Locus Rank
78
Genes in Region
GPM6A
Associated Snps
rs1106568
GWAS Region (hg19)
Genes Skipping
Ricopili Plot Surrounding Area
Distance On Each Side Of Locus In Above Plot
Ricopili Plot
Gwas And Surrounding Region Pic
Gwas Region Pic
Genes In Locus Rank
GPM6A

Sequence 1

Ensembl Gene Name
gpm6aa
Harvard Allele
a275
Mutation Area - WT DNA Sequence
ctctcaggatgtatgaagtactttcttagtatacagttatctgctatttgcaaagtattttggtatctgctacttagtgctctcctttttgttacttcgtactattttgtattctgtcatctgtttctaaattcttttctgatactcagtactaacttatgatcaacggaatcaaaaaaaccctcaaaaaattcttgattaaaagcttcttgttctaatcaagtgtatattttagatgagtatggtgacgtgtgtgttgttttctcttctctcagGATGTATGGAGTGCTGTCTGAAATGTCTAGGAGGAATCCCTTACCCATCGCTGATTGCCACTATACTGCTGTATGCTGGAGTAGCTCTCTTCTGTGGATGTGGACACGAAGCTCTCTCTGGAACGGTCACCATCCTCCAGAACTACTTTGAGGTGATCAGGGGACCTGGAGATGGTCTGGATGTGTTTACCATgtaagtgacagcagcacatt
Mutation Area - Mutant DNA Sequence
ctctcaggatgtatgaagtactttcttagtatacagttatctgctatttgcaaagtattttggtatctgctacttagtgctctcctttttgttacttcgtactattttgtattctgtcatctgtttctaaattcttttctgatactcagtactaacttatgatcaacggaatcaaaaaaaccctcaaaaaattcttgattaaaagcttcttgttctaatcaagtgtatattttagatgagtatggtgacgtgtgtgttgttttctcttctcttagGATGTATGGAGTGCTGTCTGAAATGTCTAGGAGGAATCCCTTACCTTACTGTGGATGTGGACACGAAGCTCTCTCTGGAACGGTCACCATCCTCCAGAACTACTTTGAGGTGATCAGGGGACCTGGAGATGGTCTGGATGTGTTTACCATgtaagtgacagcagcacatt
Guide RNA Target Sites
CTCAAAGTAGTTCTGGAGGATGG
GCTGGAGTAGCTCTCTTCTGTGG
CAGGGGACCTGGAGATGGTCTGG
Genotyping Primers
f, ctctcaggatgtatgaagtactttcttag
r, aatgtgctgctgtcacttacATGGTAAAC
Alignment of WT and Mutant Sequences w/ gRNA Targets (cyan) and Genotyping Primers (pink) Shown on WT Sequence
Allele
43bpD
WT Genotyping Size
488
WT Protein Sequence
MEEDMDEGQTQKGCMECCLKCLGGIPYPSLIATILLYAGVALFCGCGHEALSGTVTILQN
YFEVIRGPGDGLDVFTIIDIIKYVIYGIASAFFVYGILLMVEGFFTSGAIKDLYGDFKIT
TCGRCVSAWFIMLTYIFMLAWLGVTAFTSLPVFIYFNIWTICQNTTVLQGASLCLDPRQF
GVVPIGEEKTLCVGSENFFKMCESNELDMTFHLFVCALAGAGAAVIAMIHYLMVLSANWA
YVKDACKMQKYEDCKSKEEQELHDIHSTRSKERLNAYT-
Mutant Protein Sequence
MEEDMDEGQTQKGCMECCLKCLGGIPYLTVDVDTKLSLERSPSSRTTLR-
Mutant Genotyping Size
445
Ribosome Profiling Development
Transcript Plot

Sequence 2

Ensembl Gene Name
gpm6ab
Harvard Allele
a276
Mutation Area - WT DNA Sequence
ttatcttctcagGATTGACATCTTCAAGTATGTGATCTATGGAGTGGCAGCAGCTTTTTTTGTCTATGGTATTTTGCTGATGGTGGAGGGATTTTTCACCACTGGTGCCATCCGGGATCTCTATGGAGACTTCAAGATCACCACCTGTGGGCGCTGTGTTAGTGCCTGGgtaagatcagacaaccatttaaaagaactaatgcgcagaagaaggggtcagttcacccaaaaatgtatattcagtcatcatttatgcacctttgctgttattttaatacaatatgcccttctgtctttttaaggatatttaattattgtgatataaatacagtttcacaagagttttatggcaatatttgatgattttctggggagtctaacattactcaggtagagaaattaaataatcacaatgcaaaaaaaaaaaaaaaaaaagcttttcttactttgctttgtcttgtttctagtctaattatcaaagaaattcttgtagc
Mutation Area - Mutant DNA Sequence
TTATCTTCTCAGGATTGACATCTTCAAGTATGTGATCTATGGAGTGGCAGCAGCTTTTTTTGTCTATGGTATTTTGCTGATGGTGGAGGGATTTTTCACCGTGCCTGGGTAAGATCAGACAACCatttaaaagaactaatgcgcagaagaaggggtcagttcacccaaaaatgtatattcagtcatcatttatgcacctttgctgttattttaatacaatatgcccttctgtctttttaaggatatttaattattgtgatataaatacagtttcacaagagttttatggcaatatttgatgattttctggggagtctaacattactcaggtagagaaattaaataatcacaatgcaaaaaaaaaaaaaaaaaaagcttttcttactttgctttgtcttgtttctagtctaattatcaaagaaattcttgtagc
Guide RNA Target Sites
GAGATCCCGGATGGCACCAGTGG
Genotyping Primers
f, ttatcttctcagGATTGACATCTTCAAGTATG
r, gctacaagaatttctttgataattagactagaaacaagac
Alignment of WT and Mutant Sequences w/ gRNA Targets (cyan) and Genotyping Primers (pink) Shown on WT Sequence
Allele
61bpD
WT Genotyping Size
494
WT Protein Sequence
MGCSECCLKCLSGIPYASLIATILLYAGVALFCGCGHEALSG
TVTILQTYFDVVRSPVDALDVFTMIDIFKYVIYGVAAAFFVYGILLMVEGFFTTGAIRDL
YGDFKITTCGRCVSAWFIMLTYIFMLAWLGVTAFTSLPVFMYFNIWNTCQNMTLLEGSLS
SANSANLCFDLRQYGIVSIGEEKRLCADNENFKKMCESNELDLTFHLFVCALAGAGAAVI
AMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRSKERLNAYT-
Mutant Protein Sequence
MGCSECCLKCLSGIPYASLIATILLYAGVALFCGCGHEALSG
TVTILQTYFDVVRSPVDALDVFTMIDIFKYVIYGVAAAFFVYGI
LLMVEGFFTVPG-
In Situ Probe Sequence
ATCCCGTATGCCTCTCTGATCGCCACTATCCTGCTGTACGCCGGTGTTGCTCTCTTCTGTGGCTGTGGACATGAGGCTCTTTCTGGCACCGTCACCATCCTGCAGACCTACTTTGATGTCGTCCGGTCGCCTGTTGATGCCCTGGATGTCTTTACCATGATTGACATCTTCAAGTATGTGATCTATGGAGTGGCAGCAGCTTTTTTTGTCTATGGTATTTTGCTGATGGTGGAGGGATTTTTCACCACTGGTGCCATCCGGGATCTCTATGGAGACTTCAAGATCACCACCTGTGGGCGCTGTGTTAGTGCCTGGTTCATCATGCTTACTTATATCTTCATGTTGGCCTGGCTGGGAGTCACAGCCTTCACCTCTCTGCCGGTCTTCATGTACTTCAACATCTGGAACACTTGTCAGAACATGACTCTGCTGGAGGGTTCTCTCTCTTCAGCGAACAGCGCCAACCTTTGCTTTGACCTGCGTCAGTACGGAATCGTGTCCATCGGTGAAGAGAAAAGACTGTGTGCCGATAATGAAAACTTCAAGAAGATGTGTGAATCTAATGAGCTGGATCTGACGTTCCACTTGTTTGTCTGCGCTCTTGCGGGGGCTGGAGCGGCGGTTATCGCCATGGTGGTGGCCGTGTCTGTCCTCATCAATAACCACGCCAGTCTGACATCTAAGAACGCAGGGAGGTACT
Mutant Genotyping Size
433
Ribosome Profiling Development
Transcript Plot

Behavior Data

Behavior Data Summary
None
Behavior Data Description 1
Dark flash block 1 start Merged section Pvalue = 0.0303 7 hethom vs 7 homhom ribgraph_mean_ribbon_fullboutdata_dpix_a0darkflash103.png
Behavior Data Graph 1
Behavior Data Description 2
Day all prepulse tap Merged section Pvalue = 0.0233 7 hethet vs 7 homhom ribgraph_mean_ribbon_fullboutdata_dpix_dayprepulseinhibition100d.png
Behavior Data Graph 2
Behavior Data Description 3
Features of movement entire protocol Graph Pvalue = 0.0476 Merged section Pvalue = not significant 7 hethet vs 7 homhom ribgraph_mean_ribbonbout_aveboutdisp_10min_combo.png
Behavior Data Graph 3
Behavior Data Description 4
Frequency of movement entire protocol Graph Pvalue = not significant Merged section Pvalue = not significant 6 wthet vs 7 homhom ribgraph_mean_ribbonbout_dpixnumberofbouts_10min_combo.png
Behavior Data Graph 4
Behavior Data Description 5
Location in well entire protocol Graph Pvalue = 0.0321 Merged section Pvalue = 0.027 might not repeat 7 hethet vs 6 wthom ribgraph_mean_ribbonbout_averhofrac_10min_combo.png
Behavior Data Graph 5
Behavior Data Description 6
Frequency of movement Graph Pvalue = 0.001 6 wthet vs 7 homhom ribgraph_mean_ribbon_distsecper_min_day1mornstim.png
Behavior Data Graph 6
Behavior Data Description 7
Location in well Graph Pvalue = 0.001 10 homhet vs 7 homhom ribgraph_mean_ribbonbout_averhofrac_10min_day2morning.png
Behavior Data Graph 7
Behavior Data Description 8
Location in well Graph Pvalue = 0.004 7 hethet vs 6 wthom ribgraph_mean_ribbonbout_interboutaverhofrac_10min_day1taps.png
Behavior Data Graph 8
Behavior Data Description 9
PPI tap Graph Pvalue = 0.0164 15 homhet vs 11 homhom boxgraph_pd__ribgraph_mean_ribbon_totaldistanceresponse_dist_nightprepulseinhibition100b.png
Behavior Data Graph 9
Behavior Data Description 10
Strong tap Graph Pvalue = 0.00415 17 hethom vs 11 homhom boxgraph_pd__smallmovesribgraph_mean_ribbon_latencyresponse_dpix_nightprepulseinhibition102.png
Behavior Data Graph 10
Behavior Data Description 11
Tap habituation Graph Pvalue = 0.0013 17 hethom vs 11 homhom boxgraph_pd__ribgraph_mean_ribbon_fullboutdatamax_dpix_cdaytaphab102.png
Behavior Data Graph 11
Behavior Data Description 12
Weak tap Graph Pvalue = 0.00877 17 hethom vs 11 homhom boxgraph_pd__ribgraph_mean_ribbon_timeresponse_dpix_nightprepulseinhibition101.png
Behavior Data Graph 12
Behavior Data Description 13
None
Behavior Data Graph 13
None
Behavior Data Description 14
None
Behavior Data Graph 14
None