Locus Rank
38

Gene

Id
261
Gene Name
SYBU
Duplicated
False
Maternal
False
Gene Not Within Locus (Nearby
True
Gene Description
Mouse Phenotype
Additional Image
Allen Brain
Allen Regions
Zfin In Situ
Zfin Brain Areas
Published Zebrafish Pehnotype
Not In Allen Brain
False
ZFIN Link
http://zfin.org/ZDB-GENE-060929-1202
Allen Link
http://mouse.brain-map.org/gene/show/106548
More Additional Images
Papers

Locus Rank

Locus Rank
38
Genes in Region
ALDOA ASPHD1 C16orf92 DOC2A FAM57B GDPD3 HIRIP3 INO80E KCTD13 MAPK3 PPP4C SEZ6L2 TAOK2 TBX6 TMEM219 YPEL3
Associated Snps
rs12691307
GWAS Region (hg19)
chr16:29924377-30144877
Genes Skipping
ALDOA - definitely not; ASPHD1 - not in allen brain, and very unlikely; C16orf92 - nothing is known; FAM57B - hard to know, very little is known; GDPD3 - nothing in allen brain; HIRIP3 - histones; INO80E - maybe, but seems not that likely; MAPK3 - maybe; PPP4C - maybe, very unlikely; TAOK2 - maybe, but not in allen brain; TBX6 - not in allen brain, involved in development; TMEM219 - seems very unlikely, not in allen brain; YPEL3 - no.
Ricopili Plot Surrounding Area
Distance On Each Side Of Locus In Above Plot
0.2 MB
Ricopili Plot
Gwas And Surrounding Region Pic
Gwas Region Pic
Genes In Locus Rank
DOC2A
KCTD13
SYBU
SEZ6L2

Sequence 1

Ensembl Gene Name
sybu
Harvard Allele
a345
Mutation Area - WT DNA Sequence
ggagtatttacacattttcccctaccttcttagATGATACTGGATGCCCAAGCAGTCAATGTGCATCTCCAAGCAAGACTCCCTCCGGCTCTGACAACAGTTCACTGGCTTCTCCTGGACTGGGAGAGCGAAAGGTGAAGAGAGTGAGGATGAATGTGGAGGCCGAGTGGAGCGCACCGACACAGAAGCACAAGAGAGAAGAGCAGCAGCGCACATCCATCATGCATAAAGgtaactttatgtg
Mutation Area - Mutant DNA Sequence
GGAGTATTTACACATTTTCCCCTACCTTCTTAGATGATACTGGATGCCCAAGGCTCTGACAACAGTTCACTGGCTTCTCCTGGACTGGGAGAGCGAAAGGTGAAGAGAGTGAGGATGAATGTGGAGGCGCACCGACACAGAAGCACAAGAGAGAAGAGCAGCAGCGCACATCCATCATGCATAAAGgtaactttatgtg
Guide RNA Target Sites
GAGATGCACATTGACTGCTTGGG
TGAACTGTTGTCAGAGCCGGAGG
GGATGAATGTGGAGGCCGAGTGG
TCTCTCTTGTGCTTCTGTGTCGG
Genotyping Primers
f, ggagtatttacacattttcccctaccttc
r, cacataaagttacCTTTATGCATGATGG
Alignment of WT and Mutant Sequences w/ gRNA Targets (cyan) and Genotyping Primers (pink) Shown on WT Sequence
Allele
35bpD,10bpD
WT Genotyping Size
244
WT Protein Sequence
MGPLQTYEVKEKRNMRSRIPRFVLHPLRTKEKELSVSNMPLSEEESKDFDISSQHSKRTI
SPNSLSSDDTGCPSSQCASPSKTPSGSDNSSLASPGLGERKVKRVRMNVEAEWSAPTQKH
KREEQQRTSIMHKGSETDFSSSSSAGSYKTRETQLSNSAGKNLSSRSRGPHIRSLPVFKP
AGSPSAPRDAELYAPIRTPPKTPSFTNSSSCSNSSSSRRRTAPVRYHSCGDNHGIKPPNP
EQYLTPLQQKEVAIRHLKTKLRDSENTVCDRESEIEELKSQLGRMREDWIEEECHRVEAQ
LALKEARKEIKQLRQVVETMKNSLMEKDKGIQKYFIDINIQNRKLESLLHSMELAQNGCN
LQDEPTLDFICEAPESSTEAKMELELHCGEQAVEEMANSELLINDEMVNRVEILMSTAVD
SSQDGSTKIISQPGLSCLEPSVSEKSTKEHVSSIPIGAEDKGIQTDDVIYSTDLQTLLYQ
LLKLQGGGFPGLLVPSPNQSHDISSAQAPKKSQKEELPEAHEQDVAISTAQIVPSDSGLG
FSEPEVGPEFMEEMNSKNKAVVGKNHWSNNFFVDLVAVAAPVLPTVAWLYSQHGLVGGAP
VYNIASLIRGCCVMGLHSLRHVSHGPDT-
Mutant Protein Sequence
MGPLQTYEVKEKRNMRSRIPRFVLHPLRTKEKELSVSNMPLSEEESKDFDISSQHSKRTI
SPNSLSSDDTGCPRL-
Mutant Genotyping Size
199

Behavior Data

Behavior Data Summary
None
Behavior Data Description 1
Dark flash block 1 start Merged section Pvalue = not significant 39 het vs 53 hom ribgraph_mean_ribbon_fullboutdata_dpix_a0darkflash103.png
Behavior Data Graph 1
Behavior Data Description 2
Day all prepulse tap Merged section Pvalue = not significant 39 het vs 53 hom ribgraph_mean_ribbon_fullboutdata_dpix_dayprepulseinhibition100d.png
Behavior Data Graph 2
Behavior Data Description 3
Features of movement entire protocol Graph Pvalue = not significant Merged section Pvalue = not significant 39 het vs 53 hom ribgraph_mean_ribbonbout_aveboutdisp_10min_combo.png
Behavior Data Graph 3
Behavior Data Description 4
Frequency of movement entire protocol Graph Pvalue = not significant Merged section Pvalue = not significant 39 het vs 53 hom ribgraph_mean_ribbonbout_dpixnumberofbouts_10min_combo.png
Behavior Data Graph 4
Behavior Data Description 5
Location in well entire protocol Graph Pvalue = not significant Merged section Pvalue = not significant 39 het vs 53 hom ribgraph_mean_ribbonbout_averhofrac_10min_combo.png
Behavior Data Graph 5
Behavior Data Description 6
None
Behavior Data Graph 6
None
Behavior Data Description 7
None
Behavior Data Graph 7
None
Behavior Data Description 8
None
Behavior Data Graph 8
None
Behavior Data Description 9
None
Behavior Data Graph 9
None
Behavior Data Description 10
None
Behavior Data Graph 10
None
Behavior Data Description 11
None
Behavior Data Graph 11
None
Behavior Data Description 12
None
Behavior Data Graph 12
None
Behavior Data Description 13
None
Behavior Data Graph 13
None
Behavior Data Description 14
None
Behavior Data Graph 14
None